transducin

transducin
A GTP-binding protein found in the disc membrane of retinal rods and cones: of the part of the cascade involved in transduction of light to a nervous impulse. A complex of three subunits; a (39 kD), b (36 kD) and g (8 kD). Photoexcited rhodopsin interacts with transducin and promotes the exchange of GTP for GDP on the a subunit. The GTP- a subunit dissociates from the complex and activates a cGMP-phosphodiesterase by removing an inhibitory subunit. The a subunit of transducin can be ADP-ribosylated by cholera toxin and pertussis toxin.

Dictionary of molecular biology. 2004.

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  • Transducin — (also called Gt) is a heterotrimeric G protein that is naturally expressed in vertebrate retina rods and cones (a different Transducin gene is expressed in each cell type). Heterotrimeric Transducin (alpha beta gamma subunits) is activated by a… …   Wikipedia

  • Transducin — ist ein so genanntes heterotrimeres G Protein, welches in den Photorezeptorzellen der Netzhaut vorkommt. Es ist ein wesentlicher Bestandteil der visuellen Signaltransduktionskaskade. Als G Protein besteht es aus drei unterschiedlichen… …   Deutsch Wikipedia

  • transducin — noun Any of a class of proteins associated with the visual process …   Wiktionary

  • transducin — A protein that binds guanine nucleotides ( I.E., a G protein), found in retinal rods and cones, that plays a major role in signal transduction; in vertebrate rod cells it acts as a link of the photolysis of rhodopsin …   Medical dictionary

  • Transducin — Trans|du|cin [lat. transducere, traducere = überbringen, hinüberführen; ↑ in (3)], das; s; Syn.: Transductase: ein am Sehprozess beteiligtes Enzym (ein G Protein, MG 82 000) …   Universal-Lexikon

  • TLE1 — Transducin like enhancer of split 1 (E(sp1) homolog, Drosophila), also known as TLE1, is a human gene.cite web | title = Entrez Gene: TLE1 transducin like enhancer of split 1 (E(sp1) homolog, Drosophila)| url =… …   Wikipedia

  • TLE2 — Transducin like enhancer of split 2 (E(sp1) homolog, Drosophila), also known as TLE2, is a human gene.cite web | title = Entrez Gene: TLE2 transducin like enhancer of split 2 (E(sp1) homolog, Drosophila)| url =… …   Wikipedia

  • TLE1 — Transducin like enhancer of split 1 Estructura tridimensional de la proteína TLE1. HUGO …   Wikipedia Español

  • TBL3 — Transducin (beta) like 3, also known as TBL3, is a human gene.cite web | title = Entrez Gene: TBL3 transducin (beta) like 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=10607| accessdate = ] PBB Summary… …   Wikipedia

  • TLE3 — Transducin like enhancer of split 3 (E(sp1) homolog, Drosophila), also known as TLE3, is a human gene.cite web | title = Entrez Gene: TLE3 transducin like enhancer of split 3 (E(sp1) homolog, Drosophila)| url =… …   Wikipedia

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